Chronic wounds represent a significant clinical challenge, with delayed healing leading to increased morbidity and healthcare costs. Traditional assessment methods rely heavily on visual inspection and subjective scoring, which can miss underlying pathophysiological changes. Photoacoustic imaging has emerged as a promising modality for wound evaluation, offering high-resolution, depth-resolved insights into tissue oxygenation and vascular remodeling. Studies have demonstrated its ability to detect hypoxia and inflammation—key indicators of impaired healing—noninvasively and in real time. By integrating functional and molecular information, photoacoustics may enable earlier intervention and more personalized wound management strategies.